CORONARY INTERVENTION - CUREX

CUREXTM Paclitaxel Eluting PTCA Dilatation Balloon Catheter
A Novel Concept…
The CUREX Paclitaxel Drug Eluting Rapid Exchange PTCA (Percutaneous Transluminal Coronary Angioplasty) balloon catheter is balloon-tipped, drug-releasing balloon system for the treatment of coronary vessels. CUREX is designed to improve the lumen diameter and to reduce restenosis in the treatment of lesions in native coronary arteries.
The balloon section of the distal end of the catheter is coated with formulation of Paclitaxel drug and binding agent. In contact with the body liquid the hydrophilic binding agent swells and open the structure for the pressure induced fast release of paclitaxel drug into the vessel wall.
Optimum cell size and shape

Intended Use :

CUREX Paclitaxel Drug Eluting PTCA balloon Catheter is intended for treatment of atherosclerotic depositions in coronary lesions, specifically in patients with either in-stent restenosis or de novo coronary lesions with a reference vessel diameter ranging from 2.00mm to 4.50mm and lesion lengths up to 40mm and it is also intended for pre and post dilatation during coronary stent implantation for improving luminal diameter.
Paclitaxel Drug: A Proven anti-proliferative drug
Paclitaxel drug is a proven anti-proliferative drug that blocks cellular proliferation and migration. The CUREX is a coated with a safe and uniform dose of Paclitaxel for consistent vessel treatment.
Optimum cell size and shape Optimum cell size and shape

Why Paclitaxel for DEB??

Paclitaxel was identified as the primary drug for DEB because:
Highly lipophilic hence binds tissue at the target site and resists wash-out
Antiproliferative drug.
Safe and Reliable quantitative Drug deposition into the vessel wall
 

Unique Design Features of CUREX:

It is Effective
Lower restenosis rates than standard PTCA/PTA treatments
Fast recovery of endothelial function
Potential decrease in anti-platelet therapy
Potential for homogenous drug delivery to the vessel wall, unlike DES
Minimal Drug loss during inflation
Safe and Reliable quantitative Drug deposition into the vessel wall
Homogenous drug distribution
 

Technical Specification of CUREX Paclitaxel Eluting PTCA Dilatation Balloon Catheter:

Specifications of CUREX Paclitaxel Drug Eluting PTCA Dilatation Balloon Catheter

Available Balloon lengths (mm)

9, 14, 17, 20, 25, 30, 33, 38 & 41

Available Vessel Diameters (mm)

2.00 to 4.50

Drug

Paclitaxel

Drug Dose

2.3 µg/mm2

Balloon Material

Polyamide

Catheter Design

Rapid Exchange delivery system

Usable Shaft Length (cm)

140

Guidewire Compatibility

0.014”

Guiding Catheter Inner Diameter

5 Fr (0.056”) (1.4 mm) Compatible

Catheter Outer Shaft Diameter

2.70 Fr Proximally, 1.95 Fr Distally

Hydrophilic Coating

On the distal and proximal shaft of balloon delivery system

Balloon Inflation Pressure

Nominal Pressure (NP): 8 atm
Rated Burst Pressure (RBP):
16 atm (for: Balloon Diameter 2.00 to 4.00mm)
14 atm (for: Balloon Diameter 4.50)

  Download Brochure for ordering information
Indian FDA Approved
Manufacturing License Number: G/28/1395
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All rights reserved by Nano Therapeutics Pvt Ltd @ 2014