PERIPHERAL INTERVENTION - CUREX
CUREXTM Paclitaxel Eluting PTA Dilatation Balloon Catheter
A Novel Concept…
The CUREX Paclitaxel Drug Eluting Rapid Exchange PTA (Percutaneous Transluminal Angioplasty) balloon catheter is balloon-tipped, drug-releasing balloon system for the treatment of peripheral vessels. CUREX is designed to improve the lumen diameter and to reduce restenosis in the treatment of lesions in native peripheral arteries.
The balloon section of the distal end of the catheter is coated with formulation of Paclitaxel drug and binding agent. In contact with the body liquid the hydrophilic binding agent swells and open the structure for the pressure induced fast release of paclitaxel drug into the vessel wall.
Optimum cell size and shape

Intended Use :

CUREX Paclitaxel Drug Eluting PTA balloon Catheter is intended for treatment of atherosclerotic depositions in peripheral lesions, specifically in patients with either in-stent restenosis or de novo peripheral lesions with a reference vessel diameter ranging from 2.00mm to 12.00mm and lesion lengths up to 200mm and it is also intended for pre and post dilatation during peripheral stent implantation for improving luminal diameter.
Paclitaxel Drug: A Proven anti-proliferative drug
Paclitaxel drug is a proven anti-proliferative drug that blocks cellular proliferation and migration. The CUREX is a coated with a safe and uniform dose of Paclitaxel for consistent vessel treatment.
Optimum cell size and shape Optimum cell size and shape

Why Paclitaxel for DEB??

Paclitaxel was identified as the primary drug for DEB because:
Highly lipophilic hence binds to tissue at the target site and resists wash-out
Antiproliferative drug.
Safe and Reliable quantitative Drug deposition into the vessel wall
 

Unique Design Features of CUREX:

It is Effective
Lower restenosis rates than standard PTCA/PTA treatments
Fast recovery of endothelial function
Potential decrease in anti-platelet therapy
Potential for homogenous drug delivery to the vessel wall, unlike DES
Minimal Drug loss during inflation
Safe and Reliable quantitative Drug deposition into the vessel wall
Homogenous drug distribution
 

Technical Specification of CUREX Paclitaxel Eluting PTA Dilatation Balloon Catheter:

Specifications of CUREX Paclitaxel Drug Eluting PTA Dilatation Balloon Catheter

Generic Name

Paclitaxel Drug Eluting PTA Dilatation Balloon Catheter

Product Name

CUREX Paclitaxel Drug Eluting PTA Dilatation Balloon Catheter

Available Balloon lengths (mm)

19, 20, 25, 30, 33, 38, 40, 56, 60, 76, 80, 96, 100, 116, 120, 150 & 200

Available Vessel Diameters (mm)

2.00 to 12.00

Drug

Paclitaxel

Drug Dose

2.3 µg/mm2

Balloon Material

Polyn P®

Catheter Design

Rapid Exchange delivery system

Usable Shaft Length (cm)

150

Guidewire Compatibility

0.014”

Shaft Diameter

5F

Sheath Compatibility

5 F to 7F

Hydrophilic Coating

On the distal and proximal shaft of balloon delivery system

Balloon Inflation Pressure

Nominal Pressure (NP):
8 atm (for: Balloon Diameter 2.00 to 8.00mm)
7 atm (for: Balloon Diameter 8.50 to 12.00mm)
 Rated Burst Pressure (RBP):
14 atm (for: Balloon Diameter 4.00 to 6.00mm)
12 atm (for: Balloon Diameter 6.50 to 12.00mm)

 
  Download Brochure for ordering information
Indian FDA Approved
Manufacturing License Number: G/28/1395
 
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All rights reserved by Nano Therapeutics Pvt Ltd @ 2014